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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b904c749d450fce2e064d4677520116967fe98f7bfc2c93ce5127b5753a99fd0' 
  AND token = '4Q1UTLERYdy+3Q4cpm7xa9vhoh//3bcSAC00ZkK5Rdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}