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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf6ce7da8dfe6ab95bfdab5eb547cc2c077cbd581283518681bcf54fbfcf807' 
  AND token = '63JnqmNT1oNqmS8mBNBATmgbcpPhLj/6Lf76qnX/kOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}