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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f0826cd1a6bae12e9e6bdd9cf1eed7d03fc803aaf2d9b1f434568bcca322a8' 
  AND token = 'u3I0YiCfA7GS+FLzVKqU4uOrP+5GR9lzh2531ie6g34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}