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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d5d89a0f6a90786d8850dc200928b1cfbf7de35aed8fbe6781c389e9cefd4b' 
  AND token = 'eJ7JMnSSZ3UDOL8FPH6lU93WncWKx4oPefA1zdOP1jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}