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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f96fe350a3b659480ad4d263c272a3d9b4b6e0a723731b0bd2f4e546c4e4053d' 
  AND token = 'aaII+aIZabIA1LxwlR2RZWN41gzOKC1WkzdCf8pHDtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}