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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7edff75361d17b4c1336b33f8062e5c3b9e80bc0115255e088e30f5343d79d04' 
  AND token = 'cjicRpeEs+mS33TiIGVfvqQJH/RBC2kWVpciSYPZQik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}