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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd599c54b84cb8692eed306856352312bb5368b02dd823a2e0ed88fc00b75a8a' 
  AND token = 'DxElehD9n1G+ap1WqAY2y0rxZyU311SWxwbSQM3AAm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}