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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c3e64e9608045ef16771b44b5307a23e4622c0fba9eae05b47a1325de5f8140' 
  AND token = 'spW8mpnOXF4hDDIQ8uJy9gSPIh4VSe/u3ei1rVWNtM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}