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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5ad43794a2860cba6fcbe5d514ac4a6c224530c53cf06dc2cb43212d9b7824' 
  AND token = 'gnvl9bfMOIS9stvMKXj9hqZX7tLKnQOGagW5AxG2wr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}