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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e259f5665fb3085abde6982d0521348bfa4df6b9fd7b207c687f2bb1683528e5' 
  AND token = 'OfoottUL0ZseF1/Paki8fsIW5e3XHDDa+1Qxlgr10PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}