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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d0ffd19f586b00f4e7272ac08fd2d2bae32c38bd1c6e6563223ec0e063d188' 
  AND token = 'xnKY8P1o7MWdTuFQlPJlH3DpTi0v/hGGLXMNIGYY0JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}