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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9299e744308dfeb430618f80423e91c03f1dce78eb6b3d02e20d2b2de2993303' 
  AND token = 'SHgY223gt5G/AA8/Yp6toIzMTh60hMlIAucvbJTINvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}