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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8715681441dc6778b6852eeaab507c95d89b844f86f38c1f76a186711375926' 
  AND token = 'eM2ObSXZTRfhUH/b0tjTMZGWrspWru+qp71iaZNz7O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}