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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c027700b3e9a07e2074291132e8318cd83663c9c3a7081813127565247ce3f' 
  AND token = '2d/ceQFrM0SFtdejA+WXD1CM32mS7F4NjYMXRS51Tug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}