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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5819d46485dd76ece6d545026421ec57d97049c744dfe2a1e5e1a3f165fa6adc' 
  AND token = 'UV5zOcuN2cVDoRMgCRCB2qrQcqtgPKt/RTVM+w2z8R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}