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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef21b3cb0b3c0253cbebdb02547060e7bb756d5efcbd8ab4eb0e615fe052086' 
  AND token = 'WEs2XJYCM8Moea/+YjgENGRy2gSXDPNCpgWchDI4MlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}