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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5ddf5bb4a0fa6c21edaddc932a07940a82d2f66fa158e1c2d48af6bbdfb318' 
  AND token = 'rEkuB+HyxeFpdanYdghO8n+O0Z+LaxW6eTYsfxRYJgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}