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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77eeae4c5a32ad1bda3057db1f35a71a626dd061fb7ffbbbc253de04c4c2f9d8' 
  AND token = 'Z5RTgWGkKKkYiSmoXmbf2pVQSb7jx4heAgUKual8Lco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}