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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6124e9c30b8d669c44593ca0de5ff03197a6c151d56660eda013bd9dbc057b72' 
  AND token = '1cjaPGOGKWBbmb6U3oT2d9iyN7VKiZb2UxyG4tVfvnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}