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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b3b25dc7adab35ccde1c6088f263b6113ae950459f3ade3420abf705182ffe' 
  AND token = 'V2IFbJvNlzDPDnzNveDCqe1rghM7F5oodFgSTzdRyQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}