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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53890eb37c6c986f30da95d8d85d2e6a96e35672e1a514921fc773e67f2c4211' 
  AND token = 'uieP/xjUB4hlxOvu9T/yiug5YFRGJ3u6G5XemT5jDfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}