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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b49fc63e961e44e265c30acea7c473987559e5a196c2a3abcbae2a64f28963d' 
  AND token = 'hKyxpO/ffVZIaRPH7biwi0ntayiBxjUmw+tVg6X8oqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}