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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47339b45ccb321905d45cf407dc83b71d96c017f4ef3623c72c8f2193241d529' 
  AND token = '2xcF/Rqe8BEG9pQnx9OWbH+t29fo8qUI8BhRBY+XXS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}