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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0af1d9b9cea317c5a1459983c5dc3cf6d6071ca614268d38fa12b9614c9e63da' 
  AND token = 'Ji4laTyqooh6fDCc4dhcOKS7GUZMuMAyCKtSGSwb3dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}