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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c549759580c6a50bacfa831ff42a8b3fe992afa1601086b5c9b913dc7f73eb' 
  AND token = 'QjKOexEd6r5o4GY7XNqRpCHbGJH5/jRQWdWi5iw/f3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}