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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6357303eae905a71c8b58f1bbc9e7bdef1913b44acabfdd91cf688d9f6e561' 
  AND token = 'sWkLrwjFLm0N01tt/7vtjDwxqst7ANQ/DeeCCI4hXIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}