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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b76dc7b4cbb2786e32ae04a8907dcc3ed1b785324daa5786fa4aa5dea010638' 
  AND token = 'Ep9VA+fYv2xDyhNx3PQ/COb7GLiLvIqHoyNCimcxo8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}