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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0660eca807d717033346cdfdcef68afeb0fe6302313bc556486c7b000fc42f71' 
  AND token = 'sFIbmPobPRt/6E+5AWLNSElzCSqOS+NFdIs/Pn5Mo44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}