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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94906fcfce3159d6f9df6719cd33906384211e6c9f1e17cf1c1fc7acc33df452' 
  AND token = 'F0QyhgRhrpAoD/ECS7Zi9oKo5j8xwH2us9SZB2s8pzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}