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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bca5d13644436b74d6cc8e56544cc7a0200a96abfc235bbbf6fc267d71644ec' 
  AND token = 'o0OfJQ9/T5gviq+CVzmGX1IYrqxj6oDrfwCt1VI65rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}