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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ee03f3f8f05975e045f481d440c848a5d29e4e5cc9c70a21d85fc85009f5ce' 
  AND token = 'e51oi3Ao5SLA+LeKloWmeLfWBt2Uj71bvCwDCM3sKzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}