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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb46983690a9027f6c6f5c57129bf65f0d507da63a90c4ac215162303d8f6afb' 
  AND token = 'zyuory/ydIblBonjyIZrI84g+Th1+MyW4o5uzb5RvXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}