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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b90b061c29b480e9c7459f4663a37354ce91f4a2d4a6b1f83f096acf1b806f8c' 
  AND token = 'gxwj/TDnb0buif68sA9AHnuZoDNDO/XvDgNblHtOJdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}