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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9205a6bd643fc93f7068ff21a12cdc4501e8389650b0e7fc212afbeda5b3c468' 
  AND token = 'hlEffv9GQPs0zsNKFCDLiK5GLMLDam90p/uz30QKZ4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}