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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a658b01a87ed14216962247fd6c458c759c434ee232ed1ac07fb622b28db378' 
  AND token = 'nPkPbBppzbZfL4DOs/DQDJbpLcO1/9XqtczH6DrCZlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}