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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599b056665e298a1004f36f7c68f32097efd33492b93fee13cd3dfcad8b6bfcf' 
  AND token = 'padtQcfhO3Q50lgjnG8Qk7Mbc/Fo/AgecpMMbshkDPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}