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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8862c4d06b72f5a765986a0055dc4be9a2447afb3e0fcc0bb84bf35610b8508' 
  AND token = 'H2hGvHowVBltjIEWNj9jWwVwCHF0/0vW2s/5+ZMr6k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}