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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0bcf755896997a10245bad81b60a04000742736d8a3978cd86b751a158e8a31' 
  AND token = 'XmxNED7LNaX94x2jdieUDMdrXQLkryo3x/rHD4mkbJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}