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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e85c93b3a43ae280df0f900a946cbed5c7a0e59bc72a1cf4b27c081897d8c3' 
  AND token = 'mIkTh0uU79cettr1nPrAGY4Opm9vRZf4rd8pgIceS30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}