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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3d8c587f337155725b7f78104ffa6e3ba4cc6db220d2368eafcd6bfa4a012e' 
  AND token = 'a8YpCZz+Z92HhJTlieTxHQHsEo4cL/Jb5H2RxoQJXmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}