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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc765d1707f9fd22485f168b8c11d9ce741a9dee73543a978e4438238d80267' 
  AND token = 'E5eabX28LGkcfRk+hmh3bZoni4+BJG8NpW0iclcUDFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}