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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc339b0e6ec5cb436013889d6f4ae88e572b472a801652688b24400c0070d9aa' 
  AND token = 'gTLHR0x+KN61DPl6hw9o7jMRzSHkoavEsZcUP0PMmK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}