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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d21a01150a234652e24a87c1bb0b31a7860e63b4095e05bbdd21ea4523ced6d' 
  AND token = 'F9syov7WL7hqam9WxI/DKpSqNBDX6pcDDY4GF8V2SeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}