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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2cf847c42a791e56f18f334bbc26186169e683949a2bcc05e175a65a501549' 
  AND token = '1xvuUXnPcTQVcX70fr/m7isjC2f9mMCwq6cXEMTvKpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}