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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7096cd72d788fe2d78609b43054ffad3e42e2e3daf6eab9dbc437c87f6ca3817' 
  AND token = 'HXTa7d2FVTuTkhL6qqcSHrmGvL2PHDs0mOPRje+D3DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}