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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c532fea7e92a009a717d892003e9657ecad8cb9710ef6c49ccf7375c3f933c7' 
  AND token = '9CZNfuvFlssXN9QC+5MOVRZYl0YccLqrBksgYSTuHWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}