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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2c3a4b08600290aaa616b6f19c8333985190e20952059a6a517c1cb5465d35' 
  AND token = '7JgaZPY3k+llOTlA2EHG3yGebns4IIDHtBfX+br9Nys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}