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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20bc2b7d4db44a56e8976e0ed316ad146d90caa801a46d1ed9476ed7420aebd6' 
  AND token = 'eFaNUOFzdRVfmoSpWMD/sz8JvI9Jhit7qpyZ1xYEpB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}