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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71084614fe1204d6660c538a8a3b871932b77b7b1d868e24b21aba5cc0eada52' 
  AND token = 'IwsJND2N26wJFWNMC/T/euWJ3fr0vZwKYRCEYtMiAoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}