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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e225f0563fb5616b579444e0a67e18a867dfa303e8d78b2615d4adb7657e78' 
  AND token = 'gN5swMZaVCiBKi60majDDlbCucaecpX91WPTKhfolro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}